Mpox Outbreak Threat Assessment

June 18, 2025  /  TLP:CLEAR

Healthcare Ready is MONITORING for this event. We are monitoring potential concerns for supply chain disruptions and impacts on healthcare services on our Alert Hub.

Contents

• Situation Overview
• Potential Healthcare Impacts
• Mpox Resources

Situation Overview

• The World Health Organization (WHO) has extended its alert that mpox is a public health emergency of international concern. The WHO has declared mpox a public health emergency of international concern twice before; once in 2022 and again in 2024.
  • The outbreak is now affecting 25 countries across Africa with recent outbreaks in West Africa.
  • Sierra Leone has experienced near-exponential growth in mpox clade IIb cases and a new variant called G.1. As of June 6, there have been 11 deaths and more than 2,000 cases reported.
    • There have been five patients in the US (in Massachusetts, Illinois, and California) that were detected to have the G.1 variant.
  • The WHO issued a revised set of temporary recommendations to countries experiencing the transmission of mpox.
• The CDC has stated that the risk to the overall US population remains low.

Potential Healthcare Impacts

• The WHO issued a revised set of temporary recommendations to countries experiencing the transmission of mpox, which includes: emergency coordination, collaborative surveillance, safe and scalable clinical care, vaccination, reporting quarterly to WHO, and addressing any research gaps.
• The CDC has recommended vaccinations for people traveling to and from countries with clade I outbreaks. This includes Burundi, Central African Republic, Democratic Republic of the Congo, Kenya, Malawi, Republic of the Congo, Rwanda, South Sudan, Tanzania, Uganda, and Zambia.

Mpox Resources

• The Pediatric Pandemic Network has published multiple mpox and outbreak related resources which can be found below.

FOLLOW US

Sign up to receive event-specific emails for your state or states where your organization operates

 For media inquiries please reach out to Alexis Wing at news@healthcareready.org.

Healthcare Ready leverages unique relationships with government, nonprofit and medical supply chains to build and enhance the resiliency of communities before, during and after disasters.  

Healthcare Ready is approved by the Internal Revenue Service as a 501 (C)(3) tax-exempt organization, and all donations are tax deductible to the extent provided by law. Healthcare Ready's Federal Identification Number (EIN) is 46-3134601.